EAI-045
Rincian produk
Tag produk
| Ukuran Pek | Kasadiaan | Harga (USD) |
Ngaran Kimia:
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl) -N-(1,3-tiazol-2-yl)acetamide
Kode SMILES:
O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O
Kodeu InChi:
InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8 -27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
Konci InChi:
YTUFHOKUFOQRDF-UHFFFAOYSA-N
kecap konci:
EAI-045, EAI045, EAI 045, 1942114-09-1
Kalarutan:Leyur dina DMSO
Panyimpenan:0 - 4°C kanggo jangka pondok (poé ka minggu), atanapi -20°C kanggo jangka panjang (bulan)
Katerangan:
EAI045 mangrupikeun inhbitor EGFR anu kuat sareng selektif. EAI045 nargétkeun mutan EGFR anu tahan ubar anu dipilih tapi nyéépkeun reséptor tipe liar. EAI045 nyegah L858R / T790M-mutant EGFR kalawan potency low-nanomolar dina assays biokimia.
Sasaran: EGFR
