BAYANG-299
Rincian produk
Tag produk
| Ukuran Pek | Kasadiaan | Harga (USD) |
| 100 mg | Aya sasayogian | 500 |
| 500 mg | Aya sasayogian | 800 |
| 1g | Aya sasayogian | 1200 |
| Langkung Ukuran | Meunang Tanda kutip | Meunang Tanda kutip |
Ngaran Kimia:
2-(2,3-dihydro-1,3,6-trimethyl-2-oxo-1H-benzimidazol-5-yl) -6-(3-hydroxypropyl)-1H-benz[de]isoquinoline-1,3( 2H)-dion
Kode SMILES:
OCCCC1=CC=C(C(N2C3=C(C)C=C(N(C)C(N4C)=O)C4=C3)=O)C5=C1C=CC=C5C2=O
Kodeu InChi:
InChI=1S/C25H23N3O4/c1-14-12-20-21(27(3)25(32)26(20)2)13-19(14)28-23(30)17-8- 4-7-16-15(6-5-11-29)9-10-18(22(16)17)24(28)31/h4,7-10,12-13,29H,5-6, 11H2,1-3H3
Konci InChi:
OFWWWKWUCDUISA-UHFFFAOYSA-N
kecap konci:
BAY-299, BAY 299, BAY299, 2080306-23-4
Kalarutan:Leyur dina DMSO
Panyimpenan:0 - 4°C kanggo jangka pondok (poé ka minggu), atanapi -20°C kanggo jangka panjang (bulan).
Katerangan:
BAY-299 mangrupikeun inhibitor anu kuat sareng selektif tina bromodomain sareng PHD anu ngandung ramo (BRPF) protéin kulawarga BRD1 (IC50 = 6 nM), ogé katelah BRPF2, sareng bromodomain kadua faktor inisiasi transkripsi subunit TFIID 1 (TAF1; IC50). = 13 nM).1 BAY-299 nyaeta > 30 kali selektif leuwih BRPF1, BRPF3, BRD9, sareng ATAD2 sareng langkung selektif 300-melu tina BRD4.
Sasaran: BRPF