ARS-1323-Alkuna

Ngaran Kimia:

3-((4-(4-acryloylpiperazin-1-yl) -6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-2-yl)amino)-N-métil-N- (prop-2-yn-1-yl) propanamida

Kode SMILES:

O=C(N(C)CC#C)CCNC1=NC(N2CCN(C(C=C)=O)CC2)=C3C=C(Cl)C(C4=C(O)C=CC=C4F) =C(F)C3=N1

Kodeu InChi:

InChI=1S/C28H27ClF2N6O3/c1-4-11-35(3)22(40)9-10-32-28-33-26-17(27(34-28)37-14-12-36(13- 15-37)21(39)5-2)16-18(29)23(25(26)31)24-19(30)7-6-8-20(24)38/h1,5-8, 16,38H,2,9-15H2,3H3,(H,32,33,34)

Konci InChi:

FCCFZQSNDSLLMI-UHFFFAOYSA-N

kecap konci:

2436544-27-1；CAS:2436544-27-1；CAS:2436544-27-1；ARS-1323-Alkyne; ARS1323-Alkuna; ARS 1323-Alkuna; ARS-1323 Alkuna

Kalarutan:Leyur dina DMSO

Panyimpenan:Garing, poék sareng dina 0 - 4 C kanggo jangka pondok (poé ka minggu) atanapi -20 C kanggo jangka panjang (bulan ka taun).

Katerangan:

ARS-1323-alkuna, saku switch-II (S-IIP) inhibitor

Sasaran: saku switch-II (S-IIP)