Derazantinib; ARQ-087
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 10mg | Mudura | 800 |
| 100mg | Mudura | 1200 |
| 500mg | Mudura | 1800 |
| Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
(6R)-6-(2-fluorophenyl)-5,6-dihydro-N-[3-[2-[(2-methoxyethyl)amino]ethyl]phenyl]-Benzo[h]quinazolin-2-amine
SMILES Kodhi:
COCCNCCC1=CC(NC2=NC=C3C[C@@H](C4=CC=CC=C4F)C5=CC=CC=C5C3=N2)=CC=C1
InChi Code:
InChI=1S/C29H29FN4O/c1-35-16-15-31-14-13-20-7-6-8-22(17-20)33-29-32-19-21-18-26(24- 10-4-5-12-27(24)30)23-9-2-3-11-25(23)28(21)34-29/h2-12,17,19,26,31H,13- 16,18H2,1H3,(H,32,33,34)/t26-/m1/s1
InChi Key:
KPJDVVCDVBFRMU-AREMUKBSSA-N
Keyword:
Derazantinib, ARQ-087, ARQ087, ARQ 087, 1234356-69-4
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
Derazantinib, inozivikanwawo se ARQ-087, ndeyemuromo bioavailable inhibitor ye fibroblast growth factor receptor (FGFR) ine inogona kuita antineoplastic. FGFR inhibitor ARQ 087 inosungira uye inodzivisa zvakasimba basa reFGFR subtypes 1, 2 uye 3. Izvi zvinogona kukonzera kuvharwa kweFGFR-mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis uye tumor cell rufu muFGFR-overexpressing tumor cell cell. . FGFR, receptor tyrosine kinase, inokwidziridzwa mune dzakawanda bundu masero marudzi uye inoita basa rakakosha mukuwanda kwebundu cellular, kusiyanisa, angiogenesis uye kupona.
Chinangwa: FGFR
