EED226
Product Detail
Product Tags
| Pack Saizi | Kuwanikwa | Mutengo (USD) |
| 25mg | Mudura | 300 |
| 50mg | Mudura | 500 |
| 100mg | Mudura | 800 |
Chemical Name:
N-(furan-2-ylmethyl) -8-(4-(methylsulfonyl)phenyl)-[1,2,4]triazolo[4,3-c]pyrimidin-5-amine
SMILES Kodhi:
O=S(C1=CC=C(C2=CN=C(NCC3=CC=CO3)N4C2=NN=C4)C=C1)(C)=O
InChi Code:
InChI=1S/C17H15N5O3S/c1-26(23,24)14-6-4-12(5-7-14)15-10-19-17(22-1 1-20-21-16(15)22)18-9-13-3-2-8-25-13/h2-8,10-11H,9H2,1H3,(H,18,19)
InChi Key:
DYIRSNMPIZZNBK-UHFFFAOYSA-N
Keyword:
EED226, EED-226, EED 226, 2083627-02-3
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
EED226 inhibitor ine simba, inoshanda uye yakasarudzwa ye EZH2 ne EZH1 yakaongororwa maererano nehuwandu hwakawanda hwe epigenetic uye isiri-epigenetic zvinangwa. Iyo inoderedza zvine mutsindo pasi rose H3K27Me3 mucherechedzo mumaseru uye inoratidza yakasarudzika kuuraya masero mumasero anotakura heterozygous Y641N mutation. EED226 ine mwero wekupinda nekupimwa kwakayerwa muCaco-2 maseru paA→B=3.0x10-6 cm/s, ine efflux reshiyo pa7.6[1].
Chinangwa: EED226
