GSK2982772
Product Detail
Product Tags
Pack Saizi | Kuwanikwa | Mutengo (USD) |
100mg | Mudura | 500 |
500mg | Mudura | 800 |
1g | Mudura | 1200 |
Mamwe Saizi | Wana MaQuotes | Wana MaQuotes |
Chemical Name:
(S) -5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2, 4-triazole-3-carboxamide
SMILES Kodhi:
O=C(C1=NN=C(CC2=CC=CC=C2)N1)N[C@@H]3C(N(C)C4=CC=CC=C4OC3)=O
InChi Code:
InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(2 3-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24) /t14-/m0/s1
InChi Key:
LYPAFUINURXJSG-AWEZNQCLSA-N
Keyword:
GSK-2982772, GSK 2982772, GSK2982772, 1622848-92-3
Solubility:Soluble muDMSO
Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).
Tsanangudzo:
GSK2982772 iine simba uye inosarudza receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate yeKurapa kweZvirwere Zvinopisa. GSK2982772 iri, parizvino muchikamu 2a zvidzidzo zvekiriniki zve psoriasis, rheumatoid arthritis, uye ulcerative colitis. GSK2982772 inosunga zvine simba kuRIP1 ine exquisite kinase hunhu uye ine chiitiko chakanakisa mukuvharira akawanda anotsamira TNF cellular mhinduro. RIP1 yakabuda seyakakosha kumusoro kwekinase iyo yakaratidzwa kudzora kuzvimba kuburikidza nezvose zviri zviviri scaffolding uye kinase chaiwo mabasa.
Chinangwa: RIP1