GSK2982772

GSK2982772
  • Zita:GSK2982772
  • Catalog Nhamba:CPDD1123
  • Nhamba yeCAS:1622848-92-3
  • Molecular Weight:377.404
  • Chemical Formula:C20H19N5O3
  • Kutsvakurudza kwesayenzi chete, kwete kuvarwere.

    Product Detail

    Product Tags

    Pack Saizi Kuwanikwa Mutengo (USD)
    100mg Mudura 500
    500mg Mudura 800
    1g Mudura 1200
    Mamwe Saizi Wana MaQuotes Wana MaQuotes

    Chemical Name:

    (S) -5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2, 4-triazole-3-carboxamide

    SMILES Kodhi:

    O=C(C1=NN=C(CC2=CC=CC=C2)N1)N[C@@H]3C(N(C)C4=CC=CC=C4OC3)=O

    InChi Code:

    InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(2 3-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24) /t14-/m0/s1

    InChi Key:

    LYPAFUINURXJSG-AWEZNQCLSA-N

    Keyword:

    GSK-2982772, GSK 2982772, GSK2982772, 1622848-92-3

    Solubility:Soluble muDMSO

    Kuchengeta:0 - 4 ° C kwenguva pfupi (mazuva kusvika mavhiki), kana -20 ° C kwenguva refu (mwedzi).

    Tsanangudzo:

    GSK2982772 iine simba uye inosarudza receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate yeKurapa kweZvirwere Zvinopisa. GSK2982772 iri, parizvino muchikamu 2a zvidzidzo zvekiriniki zve psoriasis, rheumatoid arthritis, uye ulcerative colitis. GSK2982772 inosunga zvine simba kuRIP1 ine exquisite kinase hunhu uye ine chiitiko chakanakisa mukuvharira akawanda anotsamira TNF cellular mhinduro. RIP1 yakabuda seyakakosha kumusoro kwekinase iyo yakaratidzwa kudzora kuzvimba kuburikidza nezvose zviri zviviri scaffolding uye kinase chaiwo mabasa.

    Chinangwa: RIP1


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