GSK2982772
Fa'amatalaga Oloa
Faailoga o oloa
| Tele o le afifi | Avanoa | Tau (USD) |
| 100mg | E tele | 500 |
| 500mg | E tele | 800 |
| 1g | E tele | 1200 |
| Tele Tele | Maua Upusii | Maua Upusii |
Igoa vaila'au:
(S)-5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b]-[1,4]oxazepin-3-yl)-4H-1,2, 4-triazole-3-carboxamide
SMILES Code:
O=C(C1=NN=C(CC2=CC=CC=C2)N1)N[C@@H]3C(N(C)C4=CC=CC=C4OC3)=O
InChi Code:
InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(2 3-24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24) /t14-/m0/s1
InChi Key:
LYPAFUINURXJSG-AWEZNQCLSA-N
upu autu:
GSK-2982772, GSK 2982772, GSK2982772, 1622848-92-3
Solubility:Solu i le DMSO
Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), poo le -20°C mo taimi uumi (masina).
Fa'amatalaga:
O le GSK2982772 o se fa'ailoga malosi ma le filifilia o le Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate mo Togafitiga o Fa'ama'i Fua. GSK2982772 o loʻo i ai nei i le vaega 2a suʻesuʻega faʻapitoa mo psoriasis, gugu o le rūmatoid, ma le ulcerative colitis. GSK2982772 malosi e fusifusia i le RIP1 faʻatasi ai ma le faʻapitoa o kinase ma e sili ona lelei le gaioiga i le polokaina o le tele o tali telefoni feaveaʻi TNF. O le RIP1 ua tulaʻi mai o se kinase taua i luga o loʻo faʻaalia e faʻatonutonu ai le mumū e ala i galuega faʻapitoa e lua ma kinase.
Sini: RIP1
