CB-839
Fa'amatalaga Oloa
Faailoga o oloa
| Tele o le afifi | Avanoa | Tau (USD) |
| 100mg | E tele | 500 |
| 500mg | E tele | 800 |
| 1g | E tele | 1200 |
| Tele Tele | Maua Upusii | Maua Upusii |
Igoa vaila'au:
2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol -2-yl)acetamide
SMILES Code:
O=C(NC1=CC=C(CCCCC2=NN=C(NC(CC3=NC=CC=C3)=O)S2)N=N1)CC4=CC(OC(F)(F)F)=CC =C4
InChi Code:
InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34- 21)7-1-2-10-24- 35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8-9,11-14H,1-2,7, 10,15-16H2,(H,31,34,37)(H,32,36,38)
InChi Key:
PRAAPINBUWJLGA-UHFFFAOYSA-N
upu autu:
CB-839, CB839, CB 839, 1439399-58-2
Solubility:Solu i le DMSO
Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), poo le -20°C mo taimi uumi (masina).
Fa'amatalaga:
"CB-839 a o le faʻaogaina o le gutu o le glutaminase, faʻatasi ai ma le gaioiga antineoplastic. I luga o le tuʻuina atu o le gutu, CB-839 filifilia ma le le mafai ona faʻaaogaina le glutaminase, o se enzyme mitochondrial e taua mo le liua o le amino acid glutamine i le glutamate. fa'aogaina, fa'atuputeleina i sela fa'avavevave fa'aletonu e fa'alagolago i le fa'aliliuina o le glutamine i fafo i le glutamate ma le glutamate metabolites e maua uma ai le malosi ma faʻatupuina poloka fale mo le gaosiga o macromolecules, lea e manaʻomia mo le tuputupu aʻe ma le ola.
Sini: Glutaminase
