BAZ2-ICR
Fa'amatalaga Oloa
Faailoga o oloa
| Tele o le afifi | Avanoa | Tau (USD) |
| 100mg | E tele | 500 |
| 500mg | E tele | 800 |
| 1g | E tele | 1200 |
| Tele Tele | Maua Upusii | Maua Upusii |
Igoa vaila'au:
4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl) etil)-1H-imidazol-5-yl)benzonitrile
SMILES Code:
CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2
InChi Code:
InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27) 17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
InChi Key:
RRZVGDGTWNQAPW-UHFFFAOYSA-N
upu autu:
BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7
Solubility:Solu i le DMSO
Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), poo le -20°C mo taimi uumi (masina).
Fa'amatalaga:
BAZ2-ICR o se suʻesuʻega vailaʻau sili ona lelei mo suʻesuʻega faʻatinoga o le BAZ2 bromodomains in vitro ma in vivo. O le bromodomain o loʻo i ai polotini BAZ2A/B o loʻo taʻalo taua i le toe faʻaleleia o le chromatin ma le faʻatonutonuina o RNA e le faʻamaonia. BAZ2-ICR ei ai IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; soluble 25 mM (D2O) ma F = 70%.
Sini: BAZ2