ARS-1620
Fa'amatalaga Oloa
Faailoga o oloa
| Tele o le afifi | Avanoa | Tau (USD) |
| 100mg | E tele | 800 |
| 500mg | E tele | 1500 |
| 1g | E tele | 2000 |
| Tele Tele | Maua Upusii | Maua Upusii |
Igoa vaila'au:
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl) piperazin-1-yl) prop-2-en-1-one
SMILES Code:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
InChi Code:
InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
upu autu:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Solubility:Solu i le DMSO
Teuina:0 - 4°C mo taimi pupuu (aso i vaiaso), po'o le -20°C mo taimi uumi (masina)
Fa'amatalaga:
ARS-1620 o se prodrug fuafuaina mai ARS-853, o se malosi ma filifili S-IIP G12C inhibitor. O le ARS-1620 o lo'o fa'amoemoeina e avea o se togafiti fa'apitoa mo p.G12C KRAS mutant cancers.
Sini: KRAS (K-Ras G12C)
