ARD-2128

Nume chimic:

N-((1r,3r)-3-(3-clor-4-cianofenoxi)-2,2,4,4-tetrametilciclobutil)-4-(4-((1-(2-(2,6-dioxopiperidin)) -3-il)-1,3-dioxoizoindolin-5-il)piperidin-4-il)metil)piperazin-1-il)benzamidă

Cod SMILES:

O=C(C1C=CC(N2CCN(CC3CCN(C4C=CC5C(=O)N(C(=O)C=5C=4)C4C(=O)NC(=O)CC4)CC3)CC2)=CC =1)N[C@@H]1C(C)(C)[C@@H](OC2C=C(Cl)C(C#N)=CC=2)C1(C)C

Cod InChi:

InChI=1S/C45H50ClN7O6/c1-44(2)42(45(3,4)43(44)59-32-11-7-29(25-47)35(46)24-32)49-38( 55)28-5-8-30(9-6-28)52-21-19-50(20-22-52)26-27-15-17-51(18-16-27)31-10- 12-33-34(23-31)41(58)53(40(33)57)36-13-14-37(54)48-39(36)56/h5-12,23-24,27, 36,42-43H,13-22,26H2,1-4H3,(H,49,55)(H,48,54,56)/t36?,42-,43-

Cheie InChi:

BWDWHHAZFQBJQL-JABICJEXSA-N

Cuvânt cheie:

2222111-87-5；CAS:2222111-87-5；CAS:2222111-87-5；ARD-2128；ARD 2128；ARD2128

Solubilitate: 

Depozitare: 

Descriere:

Țintă: agent eficient de degradare a receptorului de androgeni protac (AR).