EAI-045
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
Paketi Kukula | Kupezeka | Mtengo (USD) |
Dzina la Chemical:
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide
SMILES Kodi:
O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O
InChi kodi:
InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8 -27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)
InChi Key:
YTUFHOKUFOQRDF-UHFFFAOYSA-N
Mawu ofunika:
EAI-045, EAI045, EAI 045, 1942114-09-1
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi)
Kufotokozera:
EAI045 ia wamphamvu komanso kusankha EGFR inhbitor. EAI045 ikufuna kusankha zosintha za EGFR zosamva mankhwala koma zimateteza zolandilira zakuthengo. EAI045 imaletsa L858R/T790M-mutant EGFR yokhala ndi mphamvu yochepa ya nanomolar mu kuyesa kwa biochemical.
Cholinga: EGFR