EAI-045

EAI-045
  • Dzina:EAI-045
  • Catalog No.:Mtengo wa CPDB0934
  • Nambala ya CAS:1942114-09-1
  • Kulemera kwa Molecular:383.4
  • Chemical formula:Chithunzi cha C19H14FN3O3S
  • Zofufuza zasayansi zokha, osati za odwala.

    Tsatanetsatane wa Zamalonda

    Zolemba Zamalonda

    Paketi Kukula Kupezeka Mtengo (USD)

    Dzina la Chemical:

    2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1,3-thiazol-2-yl)acetamide

    SMILES Kodi:

    O=C(NC1=NC=CS1)C(C2=CC(F)=CC=C2O)N3CC4=C(C=CC=C4)C3=O

    InChi kodi:

    InChI=1S/C19H14FN3O3S/c20-12-5-6-15(24)14(9-12)16(17(25)22-19-21-7-8 -27-19)23-10-11-3-1-2-4-13(11)18(23)26/h1-9,16,24H,10H2,(H,21,22,25)

    InChi Key:

    YTUFHOKUFOQRDF-UHFFFAOYSA-N

    Mawu ofunika:

    EAI-045, EAI045, EAI 045, 1942114-09-1

    Kusungunuka:Zosungunuka mu DMSO

    Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi)

    Kufotokozera:

    EAI045 ia wamphamvu komanso kusankha EGFR inhbitor. EAI045 ikufuna kusankha zosintha za EGFR zosamva mankhwala koma zimateteza zolandilira zakuthengo. EAI045 imaletsa L858R/T790M-mutant EGFR yokhala ndi mphamvu yochepa ya nanomolar mu kuyesa kwa biochemical.

    Cholinga: EGFR


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