Osimertinib Mesylate
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 500 mg | Zilipo | 100 |
| 1g | Zilipo | 180 |
| 5g | Zilipo | 600 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
N-(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-methoxy-5-((4-(1-methyl-1H-indol-3-yl)pyrimidin-2-yl)amino phenyl)acrylamide mesylate
SMILES Kodi:
CN(CCN(C)C)C1=CC(OC)=C(C=C1NC(C=C)=O)NC2=NC=CC(C3=CN(C)C4=C3C=CC=C4)=N2 .OS(=O)(C)=O
InChi kodi:
InChI=1S/C28H33N7O2.CH4O3S/c1-7-27(36)30-22-16-23(26(37-6)17-25(22)34(4)15-14-33(2)3) 32-28-29-13-12-21 (31-28 )20-18-35(5)24-11-9-8-10-19(20)24;1-5(2,3)4/h7-13,16-18H,1,14-15H2,2 -6H3,(H,30,36)(H,29,31,32);1H3,(H,2,3,4)
InChi Key:
FUKSNUHSJBTCFJ-UHFFFAOYSA-N
Mawu ofunika:
AZD-9291, AZD9291, AZD 9291, Tagrisso,Osimertinib Mesylate, 1421373-66-1
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi)
Kufotokozera:
Osimertinib, yomwe imadziwikanso kuti mereletinib ndi AZD-9291, ndi EGFR inhibitor ya m'badwo wachitatu, inasonyeza lonjezo mu maphunziro a preclinical ndipo imapereka chiyembekezo kwa odwala omwe ali ndi khansa yapamwamba ya m'mapapo yomwe yayamba kugonjetsedwa ndi EGFR inhibitors. AZD9291 imagwira ntchito kwambiri m'zitsanzo za preclinical ndipo imalekerera bwino nyama. Imalepheretsa kusintha kwa EGFR koyambitsa komanso kukana kwinaku ndikusunga mawonekedwe abwinobwino a EGFR omwe amapezeka m'maselo akhungu ndi m'matumbo, potero amachepetsa zovuta zomwe zimachitika ndi mankhwala omwe alipo. Osimertinib idavomerezedwa pa Nov. 2015.
Cholinga: EGFR
