GSK2982772
Tsatanetsatane wa Zamalonda
Zogulitsa Tags
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 500 |
| 500 mg | Zilipo | 800 |
| 1g | Zilipo | 1200 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
(S) -5-Benzyl-N-(5-methyl-4-oxo-2,3,4,5-tetrahydrobenzo[b] - [1,4]oxazepin-3-yl) -4H-1,2, 4-triazole-3-carboxamide
SMILES Kodi:
O=C(C1=NN=C(CC2=CC=CC=C2)N1)N[C@@H]3C(N(C)C4=CC=CC=C4OC3)=O
InChi kodi:
InChI=1S/C20H19N5O3/c1-25-15-9-5-6-10-16(15)28-12-14(20(25)27)21-19(26)18-22-17(23- 24-18)11-13-7-3-2-4-8-13/h2-10,14H,11-12H2,1H3,(H,21,26)(H,22,23,24)/t14 -/m0/s1
InChi Key:
LYPAFUINURXJSG-AWEZNQCLSA-N
Mawu ofunika:
GSK-2982772, GSK 2982772, GSK2982772, 1622848-92-3
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
GSK2982772 ndi mphamvu komanso yosankha receptor Interacting Protein 1 (RIP1) Kinase Specific Clinical Candidate for Treatment of Inflammatory Diseases. GSK2982772 ili, pakali pano mu gawo 2a maphunziro azachipatala a psoriasis, nyamakazi ya nyamakazi, ndi ulcerative colitis. GSK2982772 imamangiriza ku RIP1 yokhala ndi tsatanetsatane wa kinase ndipo imakhala ndi ntchito yabwino kwambiri poletsa mayankho ambiri amtundu wa TNF omwe amadalira. RIP1 yatuluka ngati yofunika kumtunda kwa kinase yomwe yawonetsedwa kuti imayang'anira kutupa kudzera muzochita zonse za scaffolding ndi kinase.
Cholinga: RIP1
