Chithunzi cha MDK7526HCl

Chithunzi cha MDK7526HCl
  • Dzina:MDK7526 HCL; Mapuloteni degrader 1 hydrochloride
  • Catalog No.:Mtengo wa CPDB1584
  • Nambala ya CAS:1448189-80-7
  • Kulemera kwa Molecular:467.025
  • Chemical formula:Chithunzi cha C22H31ClN4O3S
  • Zofufuza zasayansi zokha, osati za odwala.

    Tsatanetsatane wa Zamalonda

    Zolemba Zamalonda

    Paketi Kukula Kupezeka Mtengo (USD)
    100 mg Zilipo 500
    500 mg Zilipo 800
    1g Zilipo 1200
    Makulidwe Enanso Pezani Mawu Pezani Mawu

    Dzina la Chemical:

    (2S,4R) -1-((S)-2-amino-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

    SMILES Kodi:

    O=C([C@H]1N(C([C@@H](N)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C (C3=C(C)N=CS3)C=C2.[H]Cl

    InChi kodi:

    InChI=1S/C22H30N4O3S.ClH/c1-13-18(30-12-25-13)15-7-5-14(6-8-15)10-24-20(28)17-9-16( 27) 11-26 (1 7)21(29)19(23)22(2,3)4;/h5-8,12,16-17,19,27H,9-11,23H2,1-4H3,(H,24,28) ;1H/t16-,17+,19-;/m1./s1

    InChi Key:

    JYRTWGCWUBURGU-MSSRUXLCSA-N

    Mawu ofunika:

    MDK7526 HCl, Protein degrader 1 hydrochloride, MDK7526, MDK-7526, MDK 7526, 1448189-80-7

    Kusungunuka:Zosungunuka mu DMSO

    Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).

    Kufotokozera:

    MDK7526, yomwe imadziwikanso kuti VHL Ligand 1; Mapuloteni degrader 1, ndi amphamvu komanso kusankha mapuloteni degrader. MDK7526 ili ndi CAS#1448297-52-6, mchere wake wa HCl uli ndi CAS#1448189-80-7. MDK7526 ikhoza kukhala yothandiza pakuwonongeka kwa androgen receptor. MDK7526 imamanga cholandilira cha androgen kotero kuti cholandilira cha androgen chimayikidwa pafupi ndi ubiquitin ligase kuti igwire degrdn. (ndi kuletsa) kwa androgen receptor.

    Cholinga: Androgen Receptor


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