Mtengo wa CB-839
Tsatanetsatane wa Zamalonda
Zogulitsa Tags
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 500 |
| 500 mg | Zilipo | 800 |
| 1g | Zilipo | 1200 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol -2-yl) acetamide
SMILES Kodi:
O=C(NC1=CC=C(CCCCC2=NN=C(NC(CC3=NC=CC=C3)=O)S2)N=N1)CC4=CC(OC(F)(F)F)=CC =C4
InChi kodi:
InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34- 21)7-1-2-10-24- 35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8-9,11-14H,1-2,7, 10,15-16H2,(H,31,34,37)(H,32,36,38)
InChi Key:
PRAAPINBUWJLGA-UHFFFAOYSA-N
Mawu ofunika:
CB-839, CB839, CB 839, 1439399-58-2
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
"CB-839 ndi oral bioavailable inhibitor ya glutaminase, yokhala ndi mphamvu ya antiineoplastic." Pakamwa, CB-839 mosankha komanso mosasinthika imalepheretsa glutaminase, puloteni ya mitochondrial yomwe ndi yofunikira kuti asinthe amino acid glutamine mwa blocking glutamine. kugwiritsa ntchito, kuchulukana kwa ma cell omwe amakula mwachangu Zotupa zomwe zimadalira Glutamine zimadalira kusintha kwa glutamine kukhala glutamate ndi glutamate metabolites kuti zonse zipereke mphamvu ndikupanga ma macromolecules, omwe amafunikira kuti ma cell akule komanso kuti apulumuke.
Zolinga: Glutaminase
