GDC-0077
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 500 |
| 500 mg | Zilipo | 800 |
| 1g | Zilipo | 1200 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
(S) -2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4 ]oxazepin-9-yl)amino)propanamide
SMILES Kodi:
C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1
InChi kodi:
InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11) 24) 2 5-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21,26 )/t9-,12-/m0/s1
InChi Key:
SGEUNORSOZVTOL-CABZTGNLSA-N
Mawu ofunika:
GDC-0077, GDC0077, GDC 0077, 2060571-02-8
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
GDC-0077 ndi pakamwa komanso kusankha PI3K inhibitor (IC50 = 0.038 + 0.003 nM) ndi> 300-kusankha ma Class I PI3K isoforms. GDC-0077 ikuchita ntchito zake pomanga malo omangira a ATP a PI3K, potero amalepheretsa phosphorylation ya PIP2 ku PIP3.
Cholinga: PI3K
