Chithunzi cha BAZ2-ICR
Tsatanetsatane wa Zamalonda
Zolemba Zamalonda
| Paketi Kukula | Kupezeka | Mtengo (USD) |
| 100 mg | Zilipo | 500 |
| 500 mg | Zilipo | 800 |
| 1g | Zilipo | 1200 |
| Makulidwe Enanso | Pezani Mawu | Pezani Mawu |
Dzina la Chemical:
4-(4-(1-methyl-1H-pyrazol-4-yl)-1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)-1H-imidazol-5-yl)benzonitrile
SMILES Kodi:
CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2
InChi kodi:
InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24) -26(2)13-18)20(27)17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3
InChi Key:
RRZVGDGTWNQAPW-UHFFFAOYSA-N
Mawu ofunika:
BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7
Kusungunuka:Zosungunuka mu DMSO
Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).
Kufotokozera:
BAZ2-ICR ndi kafukufuku wamankhwala wabwino kwambiri pamaphunziro ogwira ntchito a BAZ2 bromodomains in vitro and in vivo. Bromodomain yomwe ili ndi mapuloteni BAZ2A/B imagwira ntchito zofunika pakukonzanso chromatin ndikuwongolera ma RNA osalemba. BAZ2-ICR ili ndi IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; kusungunuka kwa 25 mm (D2O) ndi F = 70%.
Cholinga: BAZ2