Adavivint

Adavivint
  • Dzina:Adavivint; Chithunzi cha SM04690
  • Catalog No.:Chithunzi cha CPDD1633
  • Nambala ya CAS:1467093-03-3
  • Kulemera kwa Molecular:505.55
  • Chemical formula:Chithunzi cha C29H24FN7O
  • Zofufuza zasayansi zokha, osati za odwala.

    Tsatanetsatane wa Zamalonda

    Zogulitsa Tags

    Paketi Kukula Kupezeka Mtengo (USD)
    100 mg Zilipo 500
    500 mg Zilipo 800
    1g Zilipo 1200
    Makulidwe Enanso Pezani Mawu Pezani Mawu

    Dzina la Chemical:

    N-(5-{3--[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 - methylbutanamide

    SMILES Kodi:

    CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1)=O

    InChi kodi:

    InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24) 29-34 -25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9-16H,8H2,1-2H3,( H,33,38)(H,34,35)(H,36,37)

    InChi Key:

    AQDWDWAYVBQMAM-UHFFFAOYSA-N

    Mawu ofunika:

    Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3

    Kusungunuka:Zosungunuka mu DMSO

    Posungira:0 - 4 ° C kwa nthawi yochepa (masiku mpaka masabata), kapena -20 ° C kwa nthawi yaitali (miyezi).

    Kufotokozera:

    Molekyu yaying'ono yatsopano ya Wnt pathway inhibitor yokhala ndi EC50 ya 3 nM mu vitro; imapangitsa kusiyana kwa hMSC kukhala ma chondrocyte okhwima, ogwira ntchito komanso amachepetsa ma cartilage catabolic marker; imapangitsa bwino kwambiri kuchuluka kwa histology ya Osteoarthritis Research Society International (OARSI) ndi ma biomarker mumtundu wa rodent OA.

    Cholinga: WNT


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