CB-839

CB-839
  • Nomen:CB-839
  • Catalogue No.CPDB1593
  • CAS No.:1439399-58-2
  • Pondus hypotheticum:571.57
  • Formulae chemica:C26H24F3N7O3S
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    2-(pyridin-2-yl)-N-(5-(4-(6-(2-(3-(trifluoromethoxy)phenyl)acetamido)pyridazin-3-yl)butyl)-1,3,4-thiadiazol -2-yl)acetamide

    SMILES Code:

    O=C(NC1=CC=C(CCCCC2=NN=C(NC(CC3=NC=CC=C3)=O)S2)N=N1)CC4=CC(OC(F)(F)F)=CC = C4

    InChi Code:

    InChI=1S/C26H24F3N7O3S/c27-26(28,29)39-20-9-5-6-17(14-20)15-22(37)31-21-12-11-18(33-34- 21)7-1-2-10-24-35-36-25(40-24)32-23(38)16-19-8-3-4-13-30-19/h3-6,8- 9,11-14H,1-2,7,10,15-16H2,(H,31,34,37)(H,32,36,38).

    InChi Key:

    PRAAPINBUWJLGA-UHFFFAOYSA-N

    Keyword:

    CB-839, CB 839, CB 839, 1439399-58-2

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    "CB-839 vox bioavailable inhibitor glutaminasis, cum potentia antineoplasticae potentiae. Super administrationem oralem, CB-839, selective et irrevocabiliter inhibet glutaminasin, enzyme mitochondriale essentiale ad conversionem amino acidi glutamine in glutamatum claudendo. utendo, multiplicatio in cellulis rapide crescentibus imminuitur glutaminum exogenosum in metabolitis glutamatis et glutamatis utrique industriam praebent et caudices gignunt ad productionem macromoleculorum, quae requiruntur ad incrementum cellulosum et superstitem.

    Target: Glutaminase


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