TH-302; Evofosfamide
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 100mg | In Stock | 360 |
| 1g | In Stock | 1000 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
N,N'-Bis(2-bromoethyl) acidum phosphorodiamidicum (1-methyl-2-nitro-1H-imidazol-5-yl) methyl ester
SMILES Code:
O=P(NCCBr)(NCCBr)OCC1=CN=C([N+]([O-])=O)N1C
InChi Code:
InChI=1S/C9H16Br2N5O4P/c1-15-8(6-12-9(15)16(17)18)7-20-21(19,13-4-2-10)14-5-3-11/ h6H,2-5,7H2,1H3,(H2,13,14,19).
InChi Key:
UGJWRPJDTDGERK-UHFFFAOYSA-N
Keyword:
TH-302, TH302, TH 302, Evofosfamide, 918633-87-1
Solubilitas:Solutum in DMSO
Repono:0 - 4° C pro brevi termino (dies ad hebdomades), vel -20° C ad terminum longum (menses)
Descriptio:
Evofosfamide, quae TH-302 nota est, est hypoxia-prodrug actuata, constans ex phosphoramidata 2-nitroimidazoli cum actione antineoplastica potentiali conjugata. Nitroimidazolum medietas hypoxiae modificato-prodrug TH-302 fungitur felis hypoxic, dibromo isophosphoramide sinapis medietatem sinapis solvens intra regiones hypoxicas tumores. Textus normoxici parci possunt propter hypoxia-specificam huius agentis activitatem, potentialiter ad toxicitatem systemicam reducendam. Compesce pro iudiciis clinicis activis vel iudiciis clinicis clausis hoc agente utens. (NCI).
Target: DNA Alkylating Agent
