GDC-0077
Product Detail
Product Tags
| Pack Size | Availability | Pretium (USD) |
| 100mg | In Stock | 500 |
| 500mg | In Stock | 800 |
| 1g | In Stock | 1200 |
| Plus Sizes | Get Quotes | Get Quotes |
Nomen chemicum:
(S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4 ]oxazepin-9-yl)amino)propanamide
SMILES Code:
C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H](C(F)F)COC3=O)=CN2CCO4)C4=C1
InChi Code:
InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11) 24 ,26)/t9-,12-/m0/s1
InChi Key:
SGEUNORSOZVTOL-CABZTGNLSA-N
Keyword:
GDC-0077, GDC0077, GDC 0077, 2060571-02-8
Solubilitas:Solutum in DMSO
Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).
Descriptio:
GDC-0077 ore promptum est et inhibitor selectivus PI3K (IC50 = 0.038 + 0.003 nM) cum > 300-plica selectivam super alias Classis I PI3K isoformes. GDC-0077 suam operam navat ligando ad locum ligaminis ATP PI3K, inhibendo phosphorylationem PIP2 ad PIP3.
Target: PI3K
