BAZ2-ICR

BAZ2-ICR
  • Nomen:BAZ2-ICR
  • Catalogue No.CPDB1614
  • CAS No.:1665195-94-7
  • Pondus hypotheticum:357.41
  • Formulae chemica:C20H19N7
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    4-(4-(1-methyl-1H-pyrazol-4-yl) -1-(2-(1-methyl-1H-pyrazol-4-yl)ethyl)1H-imidazol-5-yl) benzonitrile

    SMILES Code:

    CN(N=C1)C=C1C2=C(C3=CC=C(C#N)C=C3)N(CCC4=CN(C)N=C4)C=N2

    InChi Code:

    InChI=1S/C20H19N7/c1-25-12-16(10-23-25)7-8-27-14-22-19(18-11-24-26(2)13-18)20(27) 17-5-3-15(9-21)4-6-17/h3-6,10-14H,7-8H2,1-2H3

    InChi Key:

    RRZVGDGTWNQAPW-UHFFFAOYSA-N

    Keyword:

    BAZ2-ICR, BAZ2ICR, BAZ2 ICR, 1665195-94-7

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    BAZ2-ICR optimum est chemicum specillum ad studia functionis BAZ2 bromodomainorum in vitro et vivo. Bromodomain in quo servo BAZ2A/B partes essentiales agunt in chromatin retexere ac moderari RNAs non coding. BAZ2-ICR habet IC50 (BAZ2A) = 130 nM; IC50(BAZ2B) = 180 nM; logD = 1.05; solubilitas 25 mM (D2O) et F = 70%.

    Target: BAZ2


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