AZD-7594

AZD-7594
  • Nomen:AZD-7594
  • Catalogue No.CPDD1626
  • CAS No.:1196509-60-0
  • Pondus hypotheticum:606.6268
  • Formulae chemica:C32H32F2N4O6
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    3-(5-((1R,2S)-2-(2,2-difluoropropanamido)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)propoxy)-1H-indazol -1-yl)-N-(tetrahydrofuran-3-yl)benzamide

    SMILES Code:

    O=C(NC1COCC1)C2=CC=CC(N3N=CC4=C3C=CC(O[C@H](C5=CC=C(OCCO6)C6=C5)[C@@H](NC(C(C) F)(F)C)=O)C)=C4)=C2

    InChi Code:

    InChI=1S/C32H32F2N4O6/c1-19(36-31(40)32(2,33)34)29(20-6-9-27-28(16-20)43-13-12-42-27) 44-25-7-8-26-22(15-25)17-35-38(26). 24-5-3-4-21(14-24)30(39)37-23-10-11-41-18-23/h3-9,14-17,19,23,29H,10-13; 18H2,1-2H3,(H,36,40)(H,37,39)/t19-,23?,29-/m0/s1

    InChi Key:

    ZZWJKLGCDHYVMB-QMQODZDESA-N

    Keyword:

    AZD-7594, AZD 7594, AZD7594, AZ13189620, AZ-13189620, AZ 13189620, 1196509-60-0

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    AZD-7594, quae etiam AZ13189620 nota est, receptaculum glucocorticoidum selectivum (GCCR) modulator est attractum. AZD-7594 in periodo II tentationum clinicarum ab AstraZeneca curatione leni ad asthma moderanda est. Est etiam in periodo I iudiciis clinicis ad medicinam longis inordinationis obstructivorum pulmonis (COPD).

    Target: GCCR


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