Adavivint

Adavivint
  • Nomen:Adavivint; SM04690
  • Catalogue No.CPDD1633
  • CAS No.:1467093-03-3
  • Pondus hypotheticum:505.55
  • Formulae chemica:C29H24FN7O
  • Investigationes scientificae tantum, non aegros.

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    Nomen chemicum:

    N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]pyridin-2-yl]-1H-indazol-5-yl}pyridin-3-yl)-3 -methylbutanamide

    SMILES Code:

    CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F))=C6)=CN=C5)C=C2)=CN= C1)=O

    InChi Code:

    InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9- 16H,8H2,1-2H3;

    InChi Key:

    AQDWDWAYVBQMAM-UHFFFAOYSA-N

    Keyword:

    Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3

    Solubilitas:Solutum in DMSO

    Repono:0 - 4°C ad terminum brevem (dies ad septimanas), vel -20°C ad terminum longi (menses).

    Descriptio:

    Novus moleculae Wnt semita inhibitor cum EC50 3 nM in vitro; differentiationem hMSC inducit in chondrocytes maturas, functiones chondrocytas et cartilagines decre- mentum camporum catabolicorum; Signanter emendavit Osteoarthritis Research Societas Internationalis (OARSI) histologiam ustulo et biomarkers in exemplar rodent OA.

    Target: WNT


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