AZD7507

Nomen chemicum:

4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl) piperazino-1-yl] -7-methoxycinnolino-3-carboxamide

SMILES Code:

O=C(C1=NN=C2C=C(OC)C(N3CCN(CCO)CC3)=CC2=C1NC4=CC=C(C)C=C4F)N

InChi Code:

InChI=1S/C23H27FN6O3/c1-14-3-4-17(16(24)11-14)26-21-15-12-19(30-7-5-29(6-8-30)9- 10-31)20(33-2)13-18(15)27-28-22(21)23(25)32/h3-4,11-13,31H,5-10H2,1-2H3,(H2 ,25,32)(H,26,27)

InChi Key:

CPDGCAFPSSYOTGO-UHFFFAOYSA-N

Keyword:

AZD7507; AZD-7507; AZD 7507

Solubilitas:DMSO

Repono: 

Descriptio:

AZD7507 potens et selectiva CSF-1R inhibitor (32 nm cellae activitas), AZD7507 compositio promissa consideratur prout vim desideratam et proprietates pharmacokineticae oris AZ683 retinet. Praeterea in studio telemetriae in canibus una dosis oris data, nulla toxicitas cardiovascularis, nulla elevatio troponin ad curationem pertinentia, nullaque alteratio in ECG.

Target: CSF-1R