SEL120-34A

Aha kemịkalụ:

7,8-Dibromo-9-methyl-2-piperazin-1-yl-5,6-dihydro-4H-imidazo[4,5,1-ij] quinoline Hydrochloride

Koodu Ọchịchọ:

CC1=C(Br)C(Br)=C2CCCN3C2=C1N=C3N4CCNCC4.[H]Cl

Koodu InChi:

InChI=1S/C15H18Br2N4.ClH/c1-9-11(16)12(17)10-3-2-6-21-14(10)13(9)19-15(21)20-7-4- 18-5-8-20;/h18H,2-8H2,1H3;1H

Igodo InChi:

GQXLWUCQESKBSC-UHFFFAOYSA-N

Okwu:

SEL120-34A; SEL 120-34A; SEL-120-34A; SEL12034A; SEL 12034A; SEL-12034A

Solubility: 

Nchekwa: 

Nkọwa:

SEL120-34A bụ onye na-egbochi CDK8 dị ike ma họrọ nke na-arụ ọrụ na sel AML nwere ọkwa dị elu nke serine phosphorylation nke STAT1 na STAT5 ngalaba transactivation. EL120-34A na-egbochi phosphorylation nke STAT1 S727 na STAT5 S726 na mkpụrụ ndụ kansa na vitro. N'oge niile, a hụla ụkpụrụ nke STATs- na NUP98-HOXA9-edegharị ederede dabere dị ka usoro kachasị eme ihe na vivo.

Aha njirimara: CDK8