Riviciclib

Aha kemịkalụ:

2- (2-chlorophenyl) -5,7-dihydroxy-8- ((2R,3S) -2- (hydroxymethyl) -1-methylpyrrolidin-3-yl) -4H-chromen-4-otu hydrochloride.

Koodu Ọchịchọ:

O=C1C=C(C2=CC=CC=C2Cl)OC3=C1C(O)=CC(O)=C3[C@H]4[C@H](CO)N(C)CC4.[H] Cl

Koodu InChi:

InChI=1S/C21H20ClNO5.ClH/c1-23-7-6-12(14(23)10-24)19-15(25)8-16(26)20-17(27)9-18(28- 21 (19) 20) 11-4-2-3-5-13 (11)22;/h2-5,8-9,12,14,24-26H,6-7,10H2,1H3;1H/t12 -,14+;/m1./s1

Igodo InChi:

OOVTUOCTLAERQD-OJMBIDBESA-N

Okwu:

P276-00; P-276-00; P 276-00; P-27600; P 27600; P 27600; Riviciclib, Riviciclib HCl

Solubility: 

Nchekwa: 

Nkọwa:

Riviciclib, nke a makwaara dị ka P276-00, bụ flavone na cyclin dabere kinase (CDK) inhibitor nwere ike antineoplastic ọrụ. P276-00 na-ahọrọ ma na-egbochi Cdk4/cyclin D1, Cdk1/cyclin B na Cdk9/cyclin T1, serine/threonine kinases nke na-arụ ọrụ dị mkpa na nhazi nke usoro cell na mgbasawanye cellular. Mgbochi nke kinases ndị a na-eduga na njide okirikiri cell n'oge mgbanwe G1/S, si otú ahụ na-eduga na ntinye nke apoptosis, na mgbochi nke mmụba cell tumor.

Ebumnuche: CDK