PI3K

nwamba # Aha ngwaahịa Nkọwa
CPD1573 GDC-0077 GDC-0077 bụ ihe mgbochi PI3K dị n'ọnụ nwere ọrụ antineoplastic nwere ike.
CPD1022 IP-549 IPI549 bụ ihe mgbochi PI3Kγ nwere ike na nhọrọ nwere IC50 nke 16 nM.
CPDD3857 GDC-0326 GDC-0326 bụ onye na-egbochi ike na nhọrọ nke α-Isoform nke Phosphoinotide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 na-enweta ọkwa dị elu nke nhọrọ nhọrọ karịa kinase ndị ọzọ. GDC-0326 nwere obere plasma CL na mmadụ.
CPDB0202 AZD8186 AZD8186 bụ na onye na-egbochi beta isoform nke phosphoinotide-3 kinase (PI3K), nwere ọrụ antineoplastic nwere ike.
CPDB1536 PQR530 PQR530 bụ ihe mgbochi pan-PI3K/mTORC1/2 nwere ike dị ukwuu.
CPDB1573 GDC-0077 GDC-0077 bụ ihe dị n'ọnụ yana onye na-emechi PI3K (IC50 = 0.038 + 0.003 nM) yana> 300-fold ahọpụtara karịa isoforms Klas I PI3K ndị ọzọ.
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