nwamba # | Aha ngwaahịa | Nkọwa |
CPD1573 | GDC-0077 | GDC-0077 bụ ihe mgbochi PI3K dị n'ọnụ nwere ọrụ antineoplastic nwere ike. |
CPD1022 | IP-549 | IPI549 bụ ihe mgbochi PI3Kγ nwere ike na nhọrọ nwere IC50 nke 16 nM. |
CPDD3857 | GDC-0326 | GDC-0326 bụ onye na-egbochi ike na nhọrọ nke α-Isoform nke Phosphoinotide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 na-enweta ọkwa dị elu nke nhọrọ nhọrọ karịa kinase ndị ọzọ. GDC-0326 nwere obere plasma CL na mmadụ. |
CPDB0202 | AZD8186 | AZD8186 bụ na onye na-egbochi beta isoform nke phosphoinotide-3 kinase (PI3K), nwere ọrụ antineoplastic nwere ike. |
CPDB1536 | PQR530 | PQR530 bụ ihe mgbochi pan-PI3K/mTORC1/2 nwere ike dị ukwuu. |
CPDB1573 | GDC-0077 | GDC-0077 bụ ihe dị n'ọnụ yana onye na-emechi PI3K (IC50 = 0.038 + 0.003 nM) yana> 300-fold ahọpụtara karịa isoforms Klas I PI3K ndị ọzọ. |