nwamba # | Aha ngwaahịa | Nkọwa |
CPD100230 | JBJ-04-125-02 R-isomer | |
CPD3232 | NTN21277 | NTN21277, makwaara dị ka Gefitinib dabeere PROTAC 3 bụ VHL na-ewe ọrụ PROTAC nke na-ebute mmebi nke EGFR na EGFR mutants na DC50 nke 11.7 nM na 22.3 nM maka HCC827 cell (Exon 19 del) na H3258R cell. |
CPDB3615 | Nazartinib; EGF816; NVS-816 | Nazartinib, nke a makwaara dị ka EGF816 na NVS-816, bụ ọnụ ọnụ dịnụ, enweghị ike ịgbanwe, ọgbọ nke atọ, mutant-selective epidermal growth factor receptor (EGFR) inhibitor, nwere ọrụ antineoplastic. |
CPDB0934 | EAI-045 | EAI045 bụ ihe mgbochi EGFR dị ike ma họrọ. EAI045 lekwasịrị anya ahọrọ mutant EGFR na-eguzogide ọgwụ mana ọ na-echekwa ụdị anụ ọhịa nnata. EAI045 na-egbochi L858R/T790M-mutant EGFR nwere ike dị obere na nyocha biochemical. |
CPDB0101 | Poziotib | A na-enyocha usoro ndị nwere poziotinib n'ime ule ụlọ ọgwụ maka ọgwụgwọ EGFR-mutant lung adenocarcinoma. |
CPDB0137 | Osimertinib Mesylate | Osimertinib, nke a makwaara dị ka mereletinib na AZD-9291, bụ onye na-emechi EGFR ọgbọ nke atọ, gosipụtara nkwa na ọmụmụ ihe ọmụmụ ma na-enye olileanya maka ndị ọrịa nwere ọrịa cancer akpa ume dị elu bụ ndị na-eguzogide ndị na-emechi EGFR dị adị. |