EGFR

nwamba # Aha ngwaahịa Nkọwa
CPD100230 JBJ-04-125-02 R-isomer
CPD3232 NTN21277 NTN21277, makwaara dị ka Gefitinib dabeere PROTAC 3 bụ VHL na-ewe ọrụ PROTAC nke na-ebute mmebi nke EGFR na EGFR mutants na DC50 nke 11.7 nM na 22.3 nM maka HCC827 cell (Exon 19 del) na H3258R cell.
CPDB3615 Nazartinib; EGF816; NVS-816 Nazartinib, nke a makwaara dị ka EGF816 na NVS-816, bụ ọnụ ọnụ dịnụ, enweghị ike ịgbanwe, ọgbọ nke atọ, mutant-selective epidermal growth factor receptor (EGFR) inhibitor, nwere ọrụ antineoplastic.
CPDB0934 EAI-045 EAI045 bụ ihe mgbochi EGFR dị ike ma họrọ. EAI045 lekwasịrị anya ahọrọ mutant EGFR na-eguzogide ọgwụ mana ọ na-echekwa ụdị anụ ọhịa nnata. EAI045 na-egbochi L858R/T790M-mutant EGFR nwere ike dị obere na nyocha biochemical.
CPDB0101 Poziotib A na-enyocha usoro ndị nwere poziotinib n'ime ule ụlọ ọgwụ maka ọgwụgwọ EGFR-mutant lung adenocarcinoma.
CPDB0137 Osimertinib Mesylate Osimertinib, nke a makwaara dị ka mereletinib na AZD-9291, bụ onye na-emechi EGFR ọgbọ nke atọ, gosipụtara nkwa na ọmụmụ ihe ọmụmụ ma na-enye olileanya maka ndị ọrịa nwere ọrịa cancer akpa ume dị elu bụ ndị na-eguzogide ndị na-emechi EGFR dị adị.
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