Adavivint
Pwodwi detay
Tags pwodwi
| Gwosè pake | Disponibilite | Pri (USD) |
| 100 mg | Nan Stock | 500 |
| 500 mg | Nan Stock | 800 |
| 1g | Nan Stock | 1200 |
| Plis gwosè | Jwenn Quotes | Jwenn Quotes |
Non Chimik:
N-(5-{3-[7-(3-fluorophenyl)-1H-imidazo[4,5-c]piridin-2-yl]-1H-indazol-5-yl}piridin-3-yl)-3 -methylbutanamid
Kòd SMILES:
CC(C)CC(NC1=CC(C2=CC3=C(NN=C3C(N4)=NC5=C4C(C6=CC=CC(F)=C6)=CN=C5)C=C2)=CN= C1) = O
Kòd InChi:
InChI=1S/C29H24FN7O/c1-16(2)8-26(38)33-21-10-19(12-31-13-21)17-6-7-24-22(11-17)28( 37-36-24)29-34-25-15-32-14-23(27(25)35-29)18-4-3-5-20(30)9-18/h3-7,9- 16H,8H2,1-2H3,(H,33,38)(H,34,35)(H,36,37)
InChi kle:
AQDWDWAYVBQMAM-UHFFFAOYSA-N
Mot:
Adavivint, SM04690, SM-04690, SM 04690, 1467093-03-3
Solibilite:Soluble nan DMSO
Depo:0 - 4 ° C pou kout tèm (jou a semèn), oswa -20 ° C pou tèm long (mwa).
Deskripsyon:
Yon roman ti molekil Wnt inibitè wout ak EC50 nan 3 nM nan vitro; pwovoke hMSC diferansyasyon nan kondrosit ki gen matirite, fonksyonèl ak diminye nivo makè katabolik Cartilage; siyifikativman amelyore Osteoartritis Research Society International (OARSI) nòt istoloji ak byomarkè nan yon modèl OA wonjè.
Sib: WNT
