AZD7507
Pwodwi detay
Tags pwodwi
| Gwosè pake | Disponibilite | Pri (USD) |
| 100 mg | nan stock | Jwenn quote |
| 500 mg | nan stock | Jwenn quote |
| 1g | nan stock | Jwenn quote |
Non Chimik:
4-(2-fluoro-4-methylanilino)-6-[4-(2-hydroxyethyl)piperazin-1-yl]-7-methoxycinnoline-3-carboxamide
Kòd SMILES:
O=C(C1=NN=C2C=C(OC)C(N3CCN(CCO)CC3)=CC2=C1NC4=CC=C(C)C=C4F)N
Kòd InChi:
InChI=1S/C23H27FN6O3/c1-14-3-4-17(16(24)11-14)26-21-15-12-19(30-7-5-29(6-8-30)9- 10-31)20(33-2)13-18(15)27-28-22(21)23(25)32/h3-4,11-13,31H,5-10H2,1-2H3,(H2 ,25,32)(H,26,27)
InChi kle:
CPDGCAFPSYOTGO-UHFFFAOYSA-N
Mot:
AZD7507; AZD-7507; AZD 7507
Solibilite:DMSO
Depo:
Deskripsyon:
AZD7507 se yon inibitè CSF-1R ki pisan ak selektif (32 nM aktivite selil), AZD7507 konsidere kòm yon konpoze pwomèt paske li kenbe puisans vle a ak pwopriyete farmakokinetik oral AZ683. Anplis, nan yon etid telemetrik nan chen yo te bay yon sèl dòz oral, pa te gen okenn toksisite kadyovaskilè, pa gen okenn elevasyon nan troponin ki gen rapò ak tretman an, epi pa gen okenn chanjman nan ECG la.
Sib: CSF-1R
