CHAT # | Non pwodwi | Deskripsyon |
CPD111306 | 7-bromo-2,4,6-trichloro-8-fluoroquinazoline | |
CPD113109 | ARS-1323-Alkyne | ARS-1323-alkyne, yon pòch switch-II (S-IIP) inhibiteur |
CPDP801183 | VVD-214;RO7589831;VVD-133214 | VVD-214 se yon inibitè alosterik letal WRN helicase sentetik. |
CPDP801366 | Inlexisertib;DCC-3116 | DCC-3116 se yon inibitè ULK1/2 aktif oralman. |
CPDA601378 | Nonylacridine zoranj | |
CPD112537 | 4H-1,3-Dioxolo[4,5-c]pyrrole-4-carboxylic asid,... | |
CPDP801763 | MC3138 | MC3138 se yon activator selektif SIRT5. |
CPDP801758 | Chk1-IN-6 | Chk1-IN-6 se yon inibitè kandida CHK1 ki pisan, selektif ak oral byodisponib. |
CPD113410 | NDI-101150 | NDI-101150 se yon inibitè ki pisan ak selektif nan HPK1 (ematopoietic progenitor selil kinaz 1). |
CPDA601453 | BMS-986408 | BMS-986408 se yon oralman efikas doub DGK α/Zeta inibitè. |
CPDA601445 | AZD0780;EX-A6975;laroprovstatum; laroprovstat | PCSK9-IN-12 se yon konpoze heteroaromatic. PCSK9-IN-12 gen afinite obligatwa pou PCSK9 ak yon valè Kd<200 nM. PCSK9-IN-12 ka itilize pou etid metabolis kolestewòl. |
CPDA601447 | PF07328948 | PF-07328948 se yon inibitè oralman efikas BDK (branche chèn keton dehydrogenase kinase). |
CPD112881 | (1S) -2,2,2-trifluoro-1-methylethyl]hydrazine hy... | |
CPD108261 | LOXO-305;LY 3527727;Pirtobrutinib | Pirtobrutinib (LOXO-305) se yon inibitè BTK trè selektif ak ki pa kovalan nan pwochen jenerasyon ki ka anpeche divès kalite mitasyon sibstitisyon BTK C481. |
CPD115335 | Luxdegalutamid; ARV-766 | Luxdegalutamide (ARV-766) se yon oralman efikas idroliz pwoteyin vize chimerik (PROTAC) vize reseptè androjèn (AR), ki ka degrade mutan ki gen rapò ak rezistans AR. |
CPDA601356 | iHSP110-33 | |
CPDP800487 | TNG462 | TNG-462 se yon inibitè PRMT5 selektif oralman efikas. |
CPDP801649 | 1,2,4-Triazolo [4,3-c] pirimidin-5,8-diamine, N5... | EED ligand 1 se yon inibitè divès ak efikas ki vize sou-inite EED nan methyltransferase PRC2. |
CPDM400208 | 6,7-Difluoro-4 (3H)-quinazolinone | |
CPDP801752 | N-(4-quinolinylcarbonyl)Glycine | |
CPDM400190 | Methyl 5-bromo-2-methyl-3-(trifluorometil)benz... | |
CPDP800126 | IDE397 (GSK-4362676) | |
CPDP801185 | NST-628 | NST-628 se yon jèl molekilè MAPK ak pèmeyabilite baryè san-sèvo, ki ka anpeche fosforilasyon RAF ak aktivasyon MEK. |
CPD115153 | NX-2127 | NX-2127 se yon inibitè BTK oralman efikas. |