MC180295

Inoa Kimia:

Rel-(4-amino-2-(((2S)-bicyclo[2.2.1]heptan-2-yl)amino)thiazol-5-yl)(2-nitrophenyl)methanone

SMILES Code:

O=C(C1=C(N)N=C(N[C@@H]2C(C3)CCC3C2)S1)C4=CC=CC=C4[N+]([O-])=O

Code InChi:

InChI=1S/C17H18N4O3S/c18-16-15(14(22)11-3-1-2-4-13(11)21(23)24)25-17(20-16)19-12-8- 9-5-6-10(12)7-9/h1-4,9-10,12H,5-8,18H2,(H,19,20)/t9?,10?,12-/m0/s1

Ki InChi:

JRNXAQINDCOHGS-CBINBANVSA-N

Hua'ōlelo:

Hiki ke hoʻoheheʻe: 

Waihona: 

wehewehe:

ʻO MC180295 kahi mea hoʻopiʻi CDK9 koho nui loa (IC50 = 5 nM). (MC180295 he ākea anti-cancer hana in vitro a he mea pono i loko o vivo maʻi 'aʻai kŘkohu.

Pahuhopu: CDK9