Mai ka hoʻonohonoho haʻahaʻa o hoʻokahi keʻena hana i ka makahiki 2012, aia ʻo Caerulum i kēia manawa he 5 mau hale hana maʻamau a me 2 mau hale hana hoʻokele i kālele ʻia i ka hana kemika a me hoʻokahi keʻena DMPK a me kahi lumi analytical e noho ana i kahi ākea o 1000m2. Aia i loko o kahi pūhui hoʻolālā nani i hoʻolālā ʻia he 30km wale nō mai ke kikowaena o ke kūlanakauhale ʻo Shanghai, ua maʻalahi ʻo Caerulum i nā lawelawe hoʻopuka, nā lawelawe kākoʻo ʻenehana, nā keʻena aupuni a me nā hale hana hana a me nā mea kūʻai aku kūloko. I ka makahiki 2016, ua hoʻonui ʻo Caerulum i kāna mau lawelawe a hoʻokumu i kāna hui kaikuahine, XPiscoric Inc ma Sichuan, Chengdu e hoʻolako i nā lawelawe olaola me ka nānā ʻana i ka biological in vitro, in vivo pharmacodynamic evaluation, a me ka loiloi palekana Non-GLP. Hāʻawi pū mākou i nā mea kūʻai aku i kahi lawelawe olaola preclinical maikaʻi mai ka ʻike ʻana i ka pahuhopu a i ka loiloi palekana i ke kākoʻo ʻana i ka hoʻomohala lāʻau a me IND.
