CAT # | Inoa Huahana | wehewehe |
CPD1573 | GDC-0077 | ʻO GDC-0077 kahi mea hoʻopaneʻe PI3K i loaʻa i ka waha me ka hana antineoplastic. |
CPD1022 | IPI-549 | ʻO IPI549 kahi mea hoʻoweliweli PI3Kγ ikaika a koho me kahi IC50 o 16 nM. |
CPDD3857 | GDC-0326 | ʻO GDC-0326 kahi mea hoʻopaneʻe ikaika a koho i ka α-Isoform o Phosphoinositide 3-Kinase (PI3Kalpha inhibitor). Loaʻa iā GDC-0326 kahi kiʻekiʻe kiʻekiʻe o ka koho ma luna o nā kinases ʻē aʻe. Loaʻa iā GDC-0326 ka plasma CL haʻahaʻa i ke kanaka. |
CPDB0202 | AZD8186 | ʻO AZD8186 a me ka mea hoʻopaneʻe o ka beta isoform o phosphoinositide-3 kinase (PI3K), me ka hana antineoplastic. |
CPDB1536 | PQR530 | ʻO PQR530 kahi mea hoʻopaneʻe pan-PI3K/mTORC1/2 ikaika loa. |
CPDB1573 | GDC-0077 | ʻO GDC-0077 kahi mea hoʻopaneʻe PI3K i loaʻa i ka waha a koho ʻia (IC50 = 0.038 + 0.003 nM) me ka koho koho 300-fold ma luna o nā isoforms Class I PI3K. |