ARS-1630

ARS-1630
  • inoa:ARS-1630
  • Helu helu:CPDB2016
  • Helu CAS.:1698055-86-5
  • Kaumaha Molekala:430.84
  • ʻO ke kumu hoʻohālike kimemika:C21H17ClF2N4O2
  • No ka noiʻi ʻepekema wale nō, ʻaʻole no nā maʻi.

    Huahana Huahana

    Huahana Huahana

    Nui Puke Loaʻa Kumukuai (USD)
    100mg Loaʻa 800
    500mg Loaʻa 1500
    1g Loaʻa 2000
    Nui hou aku E kiʻi i nā huaʻōlelo E kiʻi i nā huaʻōlelo

    Inoa Kimia:

    (R)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one

    SMILES Code:

    "C=CC(N1CCN(C2=C3C=C(Cl)[C@@]([C@@]4=C(O)C=CC=C4F)=C(F)C3=NC=N2)CC1 )=O.[R]

    Code InChi:

    Ki InChi:

    Hua'ōlelo:

    ARS1630, ARS 1630, ARS-1630, 1698055-86-5

    Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

    Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)

    wehewehe:

    ʻO ARS-1630 ka R-conformational atropisomer o ARS-1620, 1,000-fold ka liʻiliʻi o ka ikaika ma mua o ARS-1620 (1.2 ± 0.6 M-1s-1) a pēlā e hana ai ma ke ʻano he hui mana ʻole ʻole.

    Pahuhopu: KRAS (K-Ras G12C)


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