ARS-1323

ARS-1323
  • inoa:ARS-1323
  • Helu helu:CPDB2015
  • Helu CAS.:1698024-73-5
  • Kaumaha Molekala:430.84
  • ʻO ke kumu hoʻohālike kimemika:C21H17ClF2N4O2
  • No ka noiʻi ʻepekema wale nō, ʻaʻole no nā maʻi.

    Huahana Huahana

    Huahana Huahana

    Nui Puke Loaʻa Kumukuai (USD)
    100mg Loaʻa 500
    500mg Loaʻa 800
    1g Loaʻa 1200
    Nui hou aku E kiʻi i nā huaʻōlelo E kiʻi i nā huaʻōlelo

    Inoa Kimia:

    1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl) prop-2-en-1-one

    SMILES Code:

    O=C(C=C)N1CCN(C2=NC=NC3=C2C=C(Cl)C(C4=C(O)C=CC=C4F)=C3F)CC1

    Code InChi:

    InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2

    Ki InChi:

    ZRPZPNYZFSJUPA-UHFFFAOYSA-N

    Hua'ōlelo:

    ARS1323, ARS 1323, ARS-1323, 1698024-73-5

    Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO

    Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina)

    wehewehe:

    ʻO ARS-1323 kahi mea hoʻopaneʻe puke o ka mutant K-ras G12C i unuhi ʻia mai ka patent WO 2015054572 A1. IC50 & Target: K-Ras G12C

    Pahuhopu: KRAS (K-Ras G12C)


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