IT-901
Huahana Huahana
Huahana Huahana
Nui Puke | Loaʻa | Kumukuai (USD) |
100mg | Loaʻa | 500 |
500mg | Loaʻa | 800 |
1g | Loaʻa | 1200 |
Nui hou aku | E kiʻi i nā huaʻōlelo | E kiʻi i nā huaʻōlelo |
Inoa Kimia:
5-[(2,4-Dimethoxy-1-naphthalenyl)methylene]dihydro-2-thioxo-4,6(1H,5H)-pyrimidinedione
SMILES Code:
O=C(/C(C(N1)=O)=CC2=C3C=CC=CC3=C(OC)C=C2OC)NC1=S
Code InChi:
InChI=1S/C17H14N2O4S/c1-22-13-8-14(23-2)11(9-5-3-4-6-10(9)13)7-12-15(20)18-17( 24)19-16(12)21/h3-8H,1-2H3,(H2,18,19,20,21,24)
Ki InChi:
JHOPCCOYRKEHQU-UHFFFAOYSA-N
huaʻōlelo:
IT-901, IT901, IT 901, 1584121-99-2
Hiki ke hoʻoheheʻe:Hiki ke hoʻoheheʻe ʻia ma DMSO
Waihona:0 - 4°C no ka wā pōkole (nā lā i nā pule), a i ʻole -20°C no ka wā lōʻihi (mau mahina).
wehewehe:
"ʻO IT-901 kahi c-Rel Inhibitor e hoʻopili ana i nā waiwai Anticancer i nā Hematologic Malignancies ma ke kāohi ʻana i ka NF-κB-Controlled Oxidative Stress Responses. IT-901 potently inhibits the NF-κB subunit c-Rel. IT-901 suppressed graft-versus- maʻi hoʻokipa ʻoiai e mālama ana i ka hana graft-versus-lymphoma i ka wā o ka hoʻololi ʻana o allogeneic no ka mālama ʻana i ka lymphoma B-cell kanaka i hōʻike ʻia i nā waiwai antitumor in vitro a i loko o ka vivo me ka ʻole o ka NF-κB-dependent lymphoma. 901 ʻaʻole i hoʻonui i ka nui o nā ʻano oxygen reactive i nā leukocytes maʻamau, e hōʻike ana i kāna mau mea koho maʻi maʻi ʻo IT-901 he mea lapaʻau no ka mālama ʻana i nā maʻi lymphoid kanaka a me ka hoʻomaikaʻi ʻana i ka maʻi graft-versus-host.
Kuhikuhi: NF-kB