Saukewa: MSC2530818
Cikakken Bayani
Tags samfurin
| Girman Kunshin | samuwa | Farashin (USD) |
| 100mg | A Stock | 400 |
| Ƙarin Girman Girma | Samu Magana | Samu Magana |
Sunan Sinadari:
[(2S) -2- (4-Chlorophenyl) pyrrolidin-1-yl] (3-methyl-1H-pyrazolo [3,4-b] pyridin-5-yl) methanone
Lambar SMILES:
O=C(N1[C@H](C2=CC=C(Cl)C=C2)CCC1)C3=CN=C(NN=C4C)C4=C3
Lambar InChi:
InChi=1S/C18H17ClN4O/c1-11-15-9-13(10-20-17(15)22-21-11)18(24)23-8-2-3-16 (23)12-4-6-14(19)7-5-12/h4-7,9-10,16H,2-3,8H2,1H3,(H,20,21,22)/t16-/ m0/s1
InChi Key:
ODRITQGYYWHQGM-INIZCTEOSA-N
Mabuɗin kalma:
MSC2530818, MSC-2530818, MSC 2530818, 1883423-59-3
Solubility:Mai narkewa a cikin DMSO
Ajiya:0 - 4°C na gajeren lokaci (kwanaki zuwa makonni), ko -20°C na dogon lokaci (watanni).
Bayani:
MSC2530818 Mai Iko ne, Zaɓaɓɓe, da Mai hana CDK8 na Baka tare da CDK8 IC50 = 2.6 nM; Hasashen PK na ɗan adam: Cl ~ 0.14 L/H/Kg; t1/2 ~ 2.4h; F> 75%. MSC2530818 yana nuna kyakkyawan zaɓi na kinase, biochemical da ƙarfin salula, kwanciyar hankali na microsomal, kuma yana iya samuwa ta baki. MSC2530818 yana nuna ƙarfin da ya dace da zaɓi don ci gaba zuwa daidaitaccen inganci a cikin tasirin vivo da nazarin aminci.
manufa: CDK
