| CAT # | Sunan samfur | Bayani |
| Saukewa: CPD100230 | JBJ-04-125-02 R-isomer | |
| Saukewa: CPD3232 | Saukewa: NTN21277 | NTN21277, wanda kuma aka sani da Gefitinib na tushen PROTAC 3 shine PROTAC mai daukar ma'aikata VHL wanda ke haifar da lalacewar EGFR da EGFR mutants tare da DC50 na 11.7 nM da 22.3 nM don tantanin halitta HCC827 (Exon 19 del) da tantanin halitta H3258R (L). |
| Saukewa: CPDB3615 | Nazartinib; EGF816; NVS-816 | Nazartinib, wanda kuma aka sani da EGF816 da NVS-816, samuwa ne ta baki, ba za a iya jurewa ba, tsararraki na uku, mai hana mai karɓar haɓakar haɓakar haɓakar mutant (EGFR), tare da yuwuwar aikin antineoplastic. |
| Saukewa: CPDB0934 | EAI-045 | EAI045 ita ce mai ƙarfi da zaɓin mai hana EGFR. EAI045 ya yi niyyar zaɓaɓɓen maye gurbi na EGFR masu jure magunguna amma yana hana mai karɓar nau'in daji. EAI045 yana hana L858R/T790M-mutant EGFR tare da ƙarancin ikon nanomolar a cikin gwajin sinadarai. |
| Saukewa: CPDB0101 | Poziotib | Ana gudanar da gwaje-gwajen da ke ɗauke da poziotinib a cikin gwaji na asibiti don maganin EGFR-mutant huhu adenocarcinoma. |
| Saukewa: CPDB0137 | Osimertinib Mesylate | Osimertinib, wanda kuma aka sani da mereletinib da AZD-9291, shine mai hanawa na EGFR na ƙarni na uku, ya nuna alƙawarin a cikin binciken da ya dace kuma yana ba da bege ga marasa lafiya da ciwon huhu na huhu waɗanda suka zama masu tsayayya ga masu hana EGFR na yanzu. |
