CAT # | Sunan samfur | Bayani |
Saukewa: CPD1573 | Saukewa: GDC-0077 | GDC-0077 shine mai hanawa na PI3K da ake samu ta baki tare da yuwuwar aikin antineoplastic. |
Saukewa: CPD1022 | Saukewa: IP-549 | IPI549 mai ƙarfi ne kuma zaɓi mai hanawa PI3Kγ tare da IC50 na 16 nM. |
Saukewa: CPDD3857 | Saukewa: GDC-0326 | GDC-0326 shine mai hanawa mai ƙarfi da zaɓi na α-Isoform na Phosphoinotide 3-Kinase (PI3Kalpha inhibitor). GDC-0326 yana samun babban matakin zaɓi akan sauran kinases. GDC-0326 yana da ƙananan plasma CL a cikin ɗan adam. |
Saukewa: CPDB0202 | Saukewa: AZD8186 | AZD8186 shine kuma mai hana beta isoform na phosphoinotide-3 kinase (PI3K), tare da yuwuwar aikin antineoplastic. |
Saukewa: CPDB1536 | Saukewa: PQR530 | PQR530 shine mai hanawa pan-PI3K/mTORC1/2 mai ƙarfi sosai. |
Saukewa: CPDB1573 | Saukewa: GDC-0077 | GDC-0077 samuwa ne ta baki kuma mai hanawa na PI3K (IC50 = 0.038 + 0.003 nM) tare da> 300-ninka zaɓaɓɓen akan sauran isoforms na Class I PI3K. |