AZD0780;EX-A6975; inbhe àrd; laroprovstat
Mion-fhiosrachadh toraidh
Bathar Tags
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Ainm Ceimigeach:
6'-(((1S,3S)-3-(5-(difluoromethoxy)pyrimidin-2-yl)amino)cyclopentyl)amino)-2H-[1,3'-bipyridin]-2-aon
Còd SMILES:
O=C1N(C=CC=C1)C2=CN=C(N[C@H]3C[C@H](CC3)NC4=NC=C(OC(F)F)C=N4)C= C2
Còd InChi:
InChI=1S/C20H20F2N6O2/c21-19(22)30-16-11-24-20(25-12-16)27-14-5-4-13(9-14)26-17-7-6- 15(10-23-17)28-8-2-1-3-18(28)29/h1-3,6-8,10-14,19H,4-5,9H2,(H,23,26 (H,24,25,27)/t13-,14-/m0/s1
iuchair InChi:
NCHUWRLOTSAFFN-KBPBESRZSA-N
Facal-luirg:
2455427-91-3 ; CAS: 2455427-91-3 ; CAS: 2455427-91-3 ;AZD0780; AZD0780; AZD0780; EX-A6975; EX-A 6975; EXA6975; laroprovstatum; laroprovstat
Solubility:
Stòradh:Tioram, dorcha agus aig 0 -4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).
Tuairisgeul:
Tha PCSK9-IN-12 na mheasgachadh heteroaromatic. Tha dàimh ceangail aig PCSK9-IN-12 ri PCSK9 le luach Kd<200 nm. Faodar PCSK9-IN-12 a chleachdadh airson sgrùdadh air metabolism cholesterol.
Targaid: PCSK9