ARS-1323-Alcaine

Ainm Ceimigeach:

3-((4-(4-acryloylpiperazin-1-yl)-6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-2-yl)amino)-N-methyl-N- (prop-2-yn-1-yl) propanamide

Còd SMILES:

O=C(N(C)CC#C)CCNC1=NC(N2CCN(C(C=C)=O)CC2)=C3C=C(Cl)C(C4=C(O)C=CC=C4F) =C(F)C3=N1

Còd InChi:

InChI=1S/C28H27ClF2N6O3/c1-4-11-35(3)22(40)9-10-32-28-33-26-17(27(34-28)37-14-12-36(13- 15-37) 21(39)5-2)16-18(29)23(25(26)31)24-19(30)7-6-8-20(24)38/h1,5-8,16,38H, 2,9-15H2,3H3,(H,32,33,34)

iuchair InChi:

FCCFZQSNDSLLMI-UHFFAOYSA-N

Facal-luirg:

2436544-27-1 ； CAS: 2436544-27-1 ； CAS: 2436544-27-1 ；ARS-1323-Alkyne; ARS1323-Ailcain; ARS 1323-Ailcain; ARS-1323 Alcaine

Solubility:Soluble ann an DMSO

Stòradh:Tioram, dorcha agus aig 0 - 4 C airson geàrr-ùine (làithean gu seachdainean) no -20 C airson ùine fhada (mìosan gu bliadhnaichean).

Tuairisgeul:

ARS-1323-alkyne, inneal-dìon pòcaid switch-II (S-IIP).

Targaid: pòcaid suidse-II (S-IIP)