GDC-0077

Ainm Ceimigeach:

(S)-2-((2-((S)-4-(difluoromethyl)-2-oxooxazolidin-3-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4 ]oxazepin-9-yl) amino) propanamide

Còd SMILES:

C[C@@H](C(N)=O)NC1=CC=C(C2=NC(N3[C@H)(C(F)F)COC3=O)=CN2CCO4)C4=C1

Còd InChi:

InChI=1S/C18H19F2N5O4/c1-9(16(21)26)22-10-2-3-11-13(6-10)28-5-4-24-7-14(23-17(11)) 24) 25-12(15(19)20)8-29-18(25)27/h2-3,6-7,9,12,15,22H,4-5,8H2,1H3,(H2,21 ,26)/t9-,12-/m0/s1

iuchair InChi:

SGEUNORSOZVTOL-CABZTGNLSA-N

Facal-luirg:

GDC-0077; GDC 0077; GDC0077

Solubility:DMSO

Stòradh: 

Tuairisgeul:

Tha GDC-0077 na neach-dìon PI3K a tha ri fhaighinn gu beòil le gnìomhachd antineoplastic a dh’ fhaodadh a bhith ann. Tha GDC-0077 air a thoirt a-mach à patent WO 2017001645 A1, foirmle I.

Targaid: PI3K