ARD-2128

Chemischer Name:

N-((1r,3r)-3-(3-chlor-4-cyanophenoxy)-2,2,4,4-tetramethylcyclobutyl)-4-(4-((1-(2-(2,6-dioxopiperidin). -3-yl)-1,3-dioxoisoindolin-5-yl)piperidin-4-yl)methyl)piperazin-1-yl)benzamid

SMILES-Code:

O=C(C1C=CC(N2CCN(CC3CCN(C4C=CC5C(=O)N(C(=O)C=5C=4)C4C(=O)NC(=O)CC 4)CC3)CC2)=CC=1)N[C@@H]1C(C)(C)[C@@H](OC2C=C(Cl)C(C#N)=CC=2)C1 (C)C

InChi-Code:

InChI=1S/C45H50ClN7O6/c1-44(2)42(45(3,4)43(44)59-32-11-7-29(25-47)35(46) 24-32)49-38(55)28-5-8-30(9-6-28)52-21-19-50(20-22-52)26-27-15-17-51(18- 16 -27)31-10-12-33-34(23-31)41(58)53(40(33)57)36-13-14-37(54)48-39(36)56/h5- 12,23-24,27,36,42-43H,13-22,26H2,1-4H3,(H,49,55)(H,48,54,56)/t36?,42-,43-

InChi-Schlüssel:

BWDWHHAZFQBJQL-JABICJEXSA-N

Stichwort:

2222111-87-5；CAS:2222111-87-5；CAS：2222111-87-5；ARD-2128；ARD 2128；ARD2128

Löslichkeit: 

Lagerung: 

Beschreibung:

Ziel: Effizienter Protac-Androgenrezeptor (AR)-abbauender Wirkstoff