GW-870086

Igama Lekhemikhali:

I-Androsta-1,4-diene-17-carboxylic acid, 6,9-difluoro-11-hydroxy-16-methyl-3-oxo-17-(((2,2,3,3-tetramethylcyclopropyl)carbonyl)oxy) -, i-cyanomethyl ester, (6alpha,11beta,16alpha,17alpha)-

Ikhodi ye-SMILES:

C[C@@]12[C@](C(OCC#N)=O)(OC(C3C(C)(C)C3(C)C)=O)[C@H](C)C[ C@@]1([H])[C@]4([H])C[C@H](F)C5=CC(C=C[C@]5(C)[C@@]4 (F)[C@@H](O)C2)=O

Ikhodi ye-InChi:

I-InChI=1S/C31H39F2NO6/c1-16-12-18-19-14-21(32)20-13-17(35)8-9-28(20,6)30(19,33)22(36) 15-29(18,7)31(16,25(38)39-11-10-34)40-24(37)23-26(2,3)27(23,4)5/h8-9, 13,16,18-19,21-23,36H,11-12,14-15H2,1-7H3/t16-,18+,19+,21+,22+,28+,29+,30+, 31+/m1/s1

I-InChi Key:

WUBKGTSFJSEIEM-NSHBDUGJSA-N

Igama elingukhiye:

GW-870086, GW870086, GW 870086, 827319-43-7

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).

Incazelo:

I-GW-870086 iyi-agonist ye-glucocorticoid receptor engase ibe ukwelashwa kwesifuba somoya kanye ne-atopic dermatitis.

Ithagethi: I-Glucocorticoid Receptor