I-BLU-554

Igama Lekhemikhali:

N-(3S,4S)-3-((6-(2,6-dichloro-3,5-dimethoxyphenyl)quinazolin-2-yl)amino)tetrahydro-2H-pyran-4-yl)acrylamide

Ikhodi ye-SMILES:

C=CC(N[C@@H]1[C@H](NC2=NC=C3C=C(C4=C(Cl)C(OC)=CC(OC)=C4Cl)C=CC3=N2) COCC1)=O

Ikhodi ye-InChi:

I-InChI=1S/C24H24Cl2N4O4/c1-4-20(31)28-16-7-8-34-12-17(16)30-24-27-11-14-9-13(5-6-15( 14)29-24)21-22(25)18(32-2)10-19(33-3)23(21)26/h4-6,9-11,16-17H,1,7-8, 12H2,2-3H3,(H,28,31)(H,27,29,30)/t16-,17+/m0/s1

I-InChi Key:

MGZKYOAQVGSSGC-DLBZAZTESA-N

Igama elingukhiye:

BLU-554, BLU554, BLU-554, 1707289-21-1

Ukunyibilika:I-Soluble ku-DMSO

Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga).

Incazelo:

I-BLU-554 iyi-fibroblast growth factor receptor 4 (FGFR4) inhibitor engase ibe ukwelashwa kwe-hepatocellular carcinoma kanye ne-cholangiocarcinoma.

Ithagethi: FGFR