I-ARS-1323
Olocwaningo lwesayensi kuphela, hhayi lweziguli.
Imininingwane Yomkhiqizo
Omaka bomkhiqizo
| Usayizi Wephakethe | Ukutholakala | Intengo (USD) |
| 100mg | Kukhona kusitoki | 500 |
| 500mg | Kukhona kusitoki | 800 |
| 1g | Kukhona kusitoki | 1200 |
| Osayizi abengeziwe | Thola Izingcaphuno | Thola Izingcaphuno |
Igama Lekhemikhali:
1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-en-1-one
Ikhodi ye-SMILES:
O=C(C=C)N1CCN(C2=NC=NC3=C2C=C(Cl)C(C4=C(O)C=CC=C4F)=C3F)CC1
Ikhodi ye-InChi:
I-InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
I-InChi Key:
ZRPZPNYZFSJUPA-UHFFFAOYSA-N
Igama elingukhiye:
I-ARS1323,ARS 1323,ARS-1323, 1698024-73-5
Ukunyibilika:I-Soluble ku-DMSO
Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga)
Incazelo:
I-ARS-1323 iyi-inhibitor yenoveli ye-mutant K-ras G12C ekhishwe ku-patent WO 2015054572 A1. I-IC50 & Okuqondisiwe: K-Ras G12C
Ithagethi: KRAS (K-Ras G12C)
