I-ARS-1620
Imininingwane Yomkhiqizo
Omaka bomkhiqizo
Usayizi Wephakethe | Ukutholakala | Intengo (USD) |
100mg | Kukhona kusitoki | 800 |
500mg | Kukhona kusitoki | 1500 |
1g | Kukhona kusitoki | 2000 |
Osayizi abengeziwe | Thola Izingcaphuno | Thola Izingcaphuno |
Igama Lekhemikhali:
(S)-1-(4-(6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl)piperazin-1-yl)prop-2-zu-1-one
Ikhodi ye-SMILES:
C=CC(=O)N1CCN(CC1)C2=C3C=C(C(=C4C(=O)C=CC=C4F)C(=C3NC=N2)F)Cl
Ikhodi ye-InChi:
I-InChI=1S/C21H17ClF2N4O2/c1-2-16(30)27-6-8-28(9-7-27)21-12-10-13(22)17(19(24)20(12)25- 11-26-21)18-14(23)4-3-5-15(18)29/h2-5,10-11,29H,1,6-9H2
I-InChi Key:
QIQWMIZVWVSRAS-UHFFFAOYSA-N
Igama elingukhiye:
ARS-1620, KRAS G12C, NSCLC, ARS1620, ARS 1620, KRASG12C, 1698055-85-4
Ukunyibilika:I-Soluble ku-DMSO
Isitoreji:0 - 4°C isikhathi esifushane (izinsuku ukuya emavikini), noma -20°C isikhathi eside (izinyanga)
Incazelo:
I-ARS-1620 iwumkhiqizo oklanywe kusukela ku-ARS-853, okuyi-S-IIP G12C inhibitor enamandla futhi ekhethiwe. I-ARS-1620 kulindeleke ukuthi ibe isu lokwelapha i-p.G12C KRAS yomdlavuza oguqukayo.
Ithagethi: KRAS (K-Ras G12C)